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2 edition of investigation of the immunotoxicology of chromium, nickel and barium from inhaled metal fumes found in the catalog.

investigation of the immunotoxicology of chromium, nickel and barium from inhaled metal fumes

Luiz Querino de Araujo Caldas

investigation of the immunotoxicology of chromium, nickel and barium from inhaled metal fumes

immunotoxicological effects on the guinea-pig such as delayed hypersensitivity, immune-tolerance, immunosuppression, bronchoconstriction and cardiotoxicity....

by Luiz Querino de Araujo Caldas

  • 179 Want to read
  • 3 Currently reading

Published in Bradford .
Written in English


Edition Notes

Ph.D. thesis. Typescript.

SeriesTheses
ID Numbers
Open LibraryOL13978971M

Chapter 4 Chromium Darryl n, Lesa d, and Nathan 63 Chapter 5 Indium Mark 93 Chapter 6 Lead Michael , Jr Chapter 7 Mercury Pierluigi i Chapter 8 Nickel Ralph wicz Chapter 9 Platinum Kathleen Rodgers Chapter 10 Vanadium Mitchell Chapter 11 Iron, Zinc, and Copper. (). Chromium in Stainless Steel Welding Fume Suppresses Lung Defense Responses Against Bacterial Infection in Rats. Journal of Immunotoxicology: Vol. 4, No. 2, pp. Cited by:

  Background: Exposure to chromium and nickel salts is a poorly characterized cause of occupational asthma. Methods: We describe four patients with work-related asthma due to metallic salts. Skin–prick tests to potassium dichromate and nickel sulfate were performed. The patients underwent methacholine inhalation tests and specific inhalation challenges (SIC) with both chromium and nickel Cited by: The biological half-life of barium varies between 2 and 20 hours. Absorbed barium is mainly deposited in bones, which accounts for 93% of the body burden in man. It is mainly excreted in feces and a small part (1 to 10%) in urine. 3 - Exprimental toxicity: In the case of barium carbonate, the Lethal Dose Fifty (LD50) is.

addition, there is much emphasis on the role of inflammation in the initiation and continuation of asthma. The clinical presentation of occupational asthma can consist of an immediate reaction, a late-phase reaction, or commonly a mixture of both types [2,4].In Western red cedar cases, for example, late asthmatic reactions alone occurred in 44%, both in 49% and immediate reactions alone in.   Respiratory cancer and exposure to arsenic, chromium, nickel, and polycyclic aromatic hydrocarbons. Anthony J. Alberg, Rex C. Yung, Paul Strickland, chromium, nickel, and selected PAH-containing mixtures in selected occupations are well established as agents that are causally associated with lung cancer. Jonas. / Respiratory cancer and Cited by: 9.


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Investigation of the immunotoxicology of chromium, nickel and barium from inhaled metal fumes by Luiz Querino de Araujo Caldas Download PDF EPUB FB2

Pulmonary Immunotoxicology of Select Metals: Aluminum, Arsenic, Cadmium, Chromium, Copper, Manganese, Nickel, Vanadium, and Zinc Article in Journal of Immunotoxicology 1(1) Author: Mitchell D Cohen.

Chromium is corrosive, cytotoxic, and carcinogenic for humans and can induce acute and chronic lung tissue toxicity. The aim of this study was to investigate Cr levels in exhaled breath condensate (EBC) of workers exposed to Cr(VI) and to assess their relationship with biochemical changes in the airways by analyzing EBC biomarkers of oxidative stress, namely, hydrogen peroxide Cited by: EXPOSURE TO FUMES CONTAINING CHROMIUM AND NICKEL Similar to the effects produced by fumes from other metals.

Cause symptoms such as nausea, headaches, dizziness, and respiratory irritation. Some persons may develop a sensitivity to chromium or nickel which can result in dermatitis or skin rash.

CHRONIC (LONG TERM) EFFECTS OFFile Size: 33KB. Chromium and Nickel in Welding Fume AWS disclaims liability for any injury to persons or to property, or other damages of any nature whatsoever, whether special, indirect, consequential or compensatory, directly or indirectly resulting from the publication, use of.

Background intensity for chromium and nickel was set to μg m −3 but mg m −3 was used for welding fumes because like asbestos, welding fumes were more widespread at the shipyard.

For comparison purposes, the American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Values (TLV) for asbestos, welding fumes Cited by: Methods to Develop Inhalation Cancer Risk Estimates for Chromium and Nickel Compounds 7 known and available, the appropriate dose response value may be applied for the purposes of risk assessment.

However, for generically reported chromium emissions where there is no information. International Agency for Research on Cancer (). "Chromium, Nickel and Welding." IARC Monograph on the Evaluation of Carcinigenic Risks to Human, 49, Lyon.

Katz, S. and H. Salem (). "The toxicology of chromium with respect to its chemical speciation: a review." Journal of Applied Toxicology 13(3):   Generation rates of fumes, total chromium, and hexavalent chromium. Generation rates of total fumes, total chromium and hexavalent chromium from six types of flux-cored wires are summarized in Table 2.

At low, optimal and high levels of input power, the ranges of FGR were –, – and – mg/min, by: controls. Occupational exposure to arsenic, cadmium, chromium(III), chromium(VI), lead and nickel was assessed by teams of local industrial hygiene experts, based on detailed occupational questionnaires.

Results The ORs for RCC were (95% CI to ) for exposure to lead and (95% CI to ) for exposure to cadmium. Ann Occup Hyg. May;59(4) doi: /annhyg/meu Epub Dec Human biomonitoring of chromium and nickel from an experimental exposure to manual metal arc welding fumes of low and high alloyed by: 6.

However, what remains unclear is the role of other co-inhaled nonemphysematogenic nonoxidant inorganic constituent in disease pathogenesis. We hypothesize that in miners, inhaled trivalent chromium (Cr(3+), the only form of Cr in coal) may potentially affect lung A1AT activity in situ via Cr complexing with Met residues, and thereby exacerbate.

Chromium (Cr) is found in nature primarily as chromite ore with Cr in the trivalent [Cr(III)] form. This ore is used for manufacturing monochromates, dichromates, chromic acid, and Cr pigments, as well as Cr metal. Chromium chemicals are of great significance to the health of workers.

Background There is limited evidence regarding the exposure-effect relationship of exposure to hexavalent chromium (CrVI) and nickel (Ni) with lung cancer.

We estimated the cumulative exposure for CrVI and Ni and assessed exposure-effect relationships for lung cancer risk by sex, smoking status, and histological subtypes. Methods Fourteen case-control studies (–) from Europe Author: Thomas Behrens, Beate Pesch, Roel Vermeulen, Ann Olsson, Joachin Schüz, Lützen Portengen, Benjamin K.

A retrospective exposure assessment of asbestos, welding fumes, chromium and nickel (in welding fumes) was conducted at the Portsmouth Naval Shipyard for a nested case-control study of lung cancer risk from external ionizing radiation.

These four contaminants were included because of their potential to confound or modify the effect of a lung. Chapter Chromium General description Sources Chromium (Cr) is a grey, hard metal most commonly found in the trivalent state in nature.

Hexavalent (chromium(VI)) compounds are also found in small quantities. Chromite (FeOCr2O3) is the only ore containing a significant amount of. BARIUM AND BARIUM COMPOUNDS. REFERENCES. ASTM. Standard test method for barium in brines, seawater, and brackish water by direct-current argon plasma atomic emission spectroscopy.

Annual Book of ASTM Standards. West Conshohocken, PA: American Society for Testing and Materials, ASTM. Mar Ferna´ndez-Nieto also reported that chromium (Cr) and nickel (Ni) fumes could give rise to occupational asthma in exposed workers [8].

However, in the general population, levels of metal. T1 - Asthma and IgE antibodies induced by chromium and nickel salts. AU - Novey, Harold S.

AU - Habib, Michael. AU - Wells, Ian D. PY - / Y1 - / N2 - Metal plating with chromium and nickel has secured an occupational relation with asthma for which an Cited by: Within 5 min after the first VOLUME 72 NUMBER 4 Antibodies induced by chromium and nickel salts CHROMIUM CHALLENGE wheezing begins K> AM 'FM TIME FIG.

Asthma induced 15 min after inhalation of chromium sulfate fumes, followed by a 22% decrease in FEV. There was no change after a similar exposure to fumes of a control by: The IARC has classified chromium (VI), the most toxic form, as a carcinogen.

“[I]nhalation of chromium (VI) has been shown to cause lung cancer.” Inhalation of chromium may also cause breathing problems, such as “asthma, cough, shortness of breath, [and] wheezing.” Ingestion of chromium (VI) may increase risk of stomach tumors.

Methods to Develop Inhalation Cancer Risk Estimates for Chromium and Nickel Compounds It is important to note that the three existing URE values (i.e., derived by: IRIS, DCHS or TCEQ with values ofand (ig/m3, respectively), only vary by less than 3-fold, and that using any of these three UREs would yield roughly.Numerous metals are responsible for immunologically mediated disorders in humans (Table 1).

One of the most common is contact dermatitis, which is probably due, to delayed hypersensitivity reactions. Thus, chromium salts, nickel, cobalt, beryllium, mercury, gold salts, and platinum salts may induce contact by: hexavalent chromium, and of nickel.

The composition of the base metals, the welding materials used, and the welding processes affect the specific compounds and concen-trations found in the welding fume. IMMEDIATE EFFECTS OF OVER-EXPOSURE TO FUMES CONTAINING CHROMIUM AND NICKEL •Similar to the effects produced by fumes from other metals.